Dr. Patel,

I sell a line of CBD Oil. I have some folks interested in the CBD Oil, but they are asking me if the CBD Oil is safe to take with their prescription medications. Could you explain the use of CBD oil and possible drug interactions?

Regards,
Laura
Denver, CO

 

 

Laura,

I’m not sure what your education & training is in, but if you’re not a physician I’d seriously warn against giving people advice about prescription medications. There are a lot of dangers to playing around with prescription medications, the worst of which includes death.

In general, people taking prescription meds should consult with their doctor before getting on CBD Oil.

And, people who take certain prescription medications especially need to consult with their doctor. And, these prescription medications include,

  • abiraterone
  • ambrisentan
  • amiodarone
  • amobarbital
  • apalutamide
  • aprepitant
  • armodafinil
  • atazanavir
  • bicalutamide
  • bortezomib
  • bosentan
  • bupropion
  • butabarbital
  • butalbital
  • carbamazepine
  • carisoprodol
  • carvedilol
  • celecoxib
  • ceritinib
  • chloramphenicol
  • chlorpropamide
  • citalopram
  • clarithromycin
  • clobazam
  • clomipramine
  • clotrimazole
  • clozapine
  • cobicistat
  • conivaptan
  • conjugated estrogens
  • conjugated estrogens, vaginal
  • crizotinib
  • cyclobenzaprine
  • cyclophosphamide
  • cyclosporine
  • dabrafenib
  • dacarbazine
  • dapsone
  • darunavir
  • dasabuvir
  • delavirdine
  • desipramine
  • dexlansoprazole
  • diazepam
  • diclofenac
  • diltiazem
  • doxepin cream
  • doxycycline
  • dronabinol
  • dronedarone
  • duloxetine
  • efavirenz
  • enzalutamide
  • erythromycin base
  • erythromycin ethylsuccinate
  • erythromycin lactobionate
  • erythromycin stearate
  • escitalopram
  • eslicarbazepine acetate
  • esomeprazole
  • estradiol
  • estrogens conjugated synthetic
  • etravirine
  • fenofibrate
  • flibanserin
  • fluconazole
  • fluoxetine
  • flutamide
  • fluvastatin
  • fluvoxamine
  • fosamprenavir
  • fosphenytoin
  • fospropofol
  • fostamatinib
  • gemfibrozil
  • glimepiride
  • glipizide
  • glyburide
  • grapefruit
  • guanabenz
  • haloperidol
  • idelalisib
  • ifosfamide
  • iloperidone
  • imatinib
  • imipramine
  • indinavir
  • irinotecan
  • isoniazid
  • isotretinoin
  • itraconazole
  • ketamine
  • ketoconazole
  • lacosamide
  • lamotrigine
  • lansoprazole
  • lapatinib
  • lesinurad
  • letermovir
  • lidocaine
  • lopinavir
  • loratadine
  • lorazepam
  • losartan
  • lumacaftor/ivacaftor
  • mephobarbital
  • mestranol
  • metaxalone
  • methadone
  • methsuximide
  • metronidazole
  • mexiletine
  • miconazole oral
  • mifepristone
  • mirtazapine
  • mitotane
  • modafinil
  • montelukast
  • morphine
  • nafcillin
  • nateglinide
  • nefazodone
  • nelfinavir
  • netupitant/palonosetron
  • nevirapine
  • nicardipine
  • olanzapine
  • ombitasvir/paritaprevir/ritonavir
  • ombitasvir/paritaprevir/ritonavir & dasabuvir
  • omeprazole
  • osimertinib
  • ospemifene
  • oxcarbazepine
  • paclitaxel
  • paclitaxel protein bound
  • pantoprazole
  • pentamidine
  • pentobarbital
  • phenobarbital
  • phenytoin
  • pimozide
  • pioglitazone
  • pirfenidone
  • pomalidomide
  • posaconazole
  • progesterone intravaginal gel
  • progesterone micronized
  • propofol
  • propranolol
  • quinupristin/dalfopristin
  • rabeprazole
  • ramelteon
  • rasagiline
  • repaglinide
  • ribociclib
  • rifampin
  • rifapentine
  • riluzole
  • riociguat
  • ritonavir
  • ropinirole
  • ropivacaine
  • rosiglitazone
  • saquinavir
  • schisandra
  • secobarbital
  • selegiline
  • selexipag
  • sertraline
  • st john’s wort
  • sulfadiazine
  • sulfisoxazole
  • tacrine
  • tamoxifen
  • tasimelteon
  • tetracycline
  • theophylline
  • thiothixene
  • ticlopidine
  • tipranavir
  • tizanidine
  • tofacitinib
  • tolbutamide
  • torsemide
  • tranylcypromine
  • treprostinil
  • tretinoin
  • trifluoperazine
  • trimethoprim
  • trimipramine
  • velpatasvir
  • verapamil
  • voriconazole
  • voxilaprevir
  • warfarin
  • zafirlukast

Now, if you’re wondering why you need to consult with your doctor, there are several reasons.

  • When you’re on CBD Oil, the dosing of your prescription medications may need to adjusted.

For example, one study looked at the effects of CBD on the anti-seizure medication Clobazam. They looked to see what happened when 13 kids with Epilepsy were given Clobazam with CBD. It was found that CBD slowed the breakdown of Clobazam. Clobazam stuck around longer than normal. And, as a result, the dose of Clobazam that these kids were on had to be adjusted.

  • If you’re on a medication that affects the liver, there can be an additive toxic effect to the liver when it’s taken with CBD.

For example, in one study, patients taking CBD and Valproate – an antiseizure medication – had abnormal liver tests.

And, the study suggested that people’s liver function get monitored when they’re taking CBD in conjunction with medications that affect the liver.

Again, overall, if you’re taking any sort of prescription medications, consult with your physician prior to taking any CBD Oil.

 

 

 

 


Research Referenced: